March 12, 2007 --- Restylane® has been found to be much more than a mere "wrinkle filler," according to Dr. Andrew J. Wolfe and Dr. Steven D. Vath, board-certified plastic surgeons and Directors of the Rejuvenate! medical spa. A recent study by U. of M. Medical School researchers discovered that along with restoring a firm foundation underneath facial skin, allowing skin to lie smooth and wrinkle-free once again, the product also stimulates the body’s natural collagen-producing processes. This exciting news suggests that Restylane® has the additional potential to actually improve the quality of aging, sun-damaged skin.

Restylane®, an FDA-approved injectable gel, is based on hyaluronic acid, a natural, plant-derived substance that binds to water molecules in the skin and provides a firm support system for surface tissues. In their independent study, the U. of M. scientists found that the substance also acts on collagen-producing cells called "fibroblasts," prompting them to stretch and produce more of the all-important protein essential for youthful skin.

"This is an intriguing find by the team," said Dr. Wolfe. "It indicates that our medical spa clients who enjoy the immediate wrinkle-filling effects of the product can also anticipate improved skin tone over a period of time." Dr. Wolfe also noted that the new study boosts the value of Restylane® for patients. "After a few initial treatments, our clients may very well find they need smaller amounts of the product as their skin quality improves," he said.

More than a million wrinkle filling injections are performed in the U.S. each year, and products based on hyaluronic acid are currently very popular. Increasing attention on these treatments on the part of the media and the scientific community is good news for consumers, as the battle among manufacturers intensifies.

The U. of M. research team confined their studies to Restylane® alone. Other hyaluronic acid-based injectable treatments may also be found to have similar properties. "Dr. Vath and I will be following these developments closely," Dr. Wolfe commented, "so we can continue to offer our patients the most effective ways to look their best."